COVID-19-Related Rhino-Orbital-Cerebral Mucormycosis With Angioinvasion: A Lethal Sequelae

A middle-aged man with multiple comorbidities including uncontrolled diabetes mellitus presented shortness of breath and lethargy for six days. He was treated COVID-19 pneumonia, requiring high cumulative steroid therapy. After 15 days treatment, he developed right orbital apex syndrome central retinal artery occlusion secondary to invasive mucormycosis. The infection progressed rapidly despite aggressive medical systemic anti-fungal therapy along local transcutaneous retrobulbar amphotericin B injection. We report our battle in fighting this vicious disease. Judicious use immunomodulators treatment close monitoring is crucial, especially high-risk patients.